49ers 2025 Opponents Revealed. View the 2025 san francisco 49ers schedule at fbschedules.com. The san francisco 49ers' 2024 season is almost over and, following their monday night football loss to the detroit lions in week 17, they now know the identity of every team they will face in 2025.

San francisco 49ers’ 2025 season opponents revealed: Purdy, pearsall shine in 49ers’ loss to lions;